Neomycin Sulfate

Neomycin sulfate is an antibiotic from the aminoglycoside class, primarily used for treating local or systemic bacterial infections. It is available as a white crystalline powder, odorless, and soluble in water. Neomycin sulfate works by inhibiting bacterial protein synthesis, leading to bacterial cell death. In research, it is widely used to study mechanisms of bacterial resistance, pharmacokinetics of antibiotics, and the side effects of antimicrobial treatments.

Applications:

1. Treatment of Bacterial Infections:

   • Used to treat infections caused by Gram-negative bacteria and some Gram-positive bacteria.
   • Commonly administered for skin, intra-abdominal, and urinary tract infections.

2. Microbiological Research:

   • Studies on mechanisms of antibiotic resistance.
   • Used in cell culture to investigate antibiotic-bacteria interactions.

3. Pharmacology and Toxicology:

   • Studies the side effects of aminoglycosides, including nephrotoxicity and neurotoxicity.
   • Toxicity tests on various experimental models.