Closantel

Closantel is an antiparasitic compound from the salicylanilide family, primarily used to treat parasitic infections in animals. It is available as a white crystalline powder, odorless, and sparingly soluble in water, often incorporated into veterinary formulations. While combustible, it is minimally flammable and possesses a stable chemical structure, making it a preferred choice for laboratory research involving antiparasitics.

Applications:

1. Parasitic Treatments:

   • Effective against gastrointestinal parasites, including worms and trematodes in animals.
   • Used in veterinary research to study treatments for parasitic infections.

2. Pharmacokinetic Studies:

   • Analysis of Closantel metabolism and tissue distribution in animals.
   • Preclinical models for testing the efficacy and safety of new antiparasitic treatments.

3. Drug Resistance Models:

   • Evaluates parasite resistance to current treatments by measuring the reduced efficacy of Closantel in various biological environments.