Afoxolaner

Afoxolaner is an antiparasitic primarily used to treat and prevent parasitic infestations in animals, particularly against fleas and ticks. It is presented as a white crystalline powder, odorless, weakly soluble in water, and slightly soluble in organic solvents. It is classified as a lipophilic compound and stable under normal storage conditions. Afoxolaner works by blocking chloride channels and inhibiting neurotransmission in parasites, leading to their paralysis and elimination.

Applications:

Antiparasitic treatment for animals:

• Effective against fleas, ticks, and other external parasites.
• Used in oral treatments for controlling parasitic infestations in dogs and cats.

Veterinary research:

• Studies on the mechanisms of action of antiparasitics.
• Used in research to develop new treatments and solutions for resistant parasites.

Veterinary external care products:

• Integrated into topical and oral formulations for the prevention and control of parasitic infestations in pets.